Way Seen to Counter Blood-clotting Molecule That Blocks Myelin Repair

Study by the Akassoglou Lab showed that blocking a particular receptor protein of the BMP signaling pathway, effectively promoted the maturation of myelin-producing cells and myelin repair. To read the full article, click here.


New Line of Drugs Could Help Promote Brain Repair in Multiple Sclerosis

Members of Akassoglou Lab working on a new study for new line of drugs to potentially stimulate myelin repair in the presence of toxic blood leaks in the brain. To view the full article, click here. 

Brain Selected Our Image For The August 2021 Volume

Illustration by Ella Marushchenko

The Akassoglou Lab showed toxic blood leaks in the brain inhibiting remyelination with implications for the development of therapeutic strategies for neuro-repair in multiple sclerosis and other neurological diseases with blood-brain barrier disruption and myelin damage. From Petersen et al. BMP receptor blockade overcomes extrinsic inhibition of remyelination and restores neurovascular homeostasis. Pp. 2291-2301.

Overcoming obstacles to promote repair in multiple sclerosis

Scientists at Akassoglou Lab identifying toxic elements that inhibit repair of damaged myelin and producing studies to find new treatments. To view full article click here.

Zhaoqi Yan – BrightFocus Alzheimer’s Disease Research Program Award Recipient

Since 1985, the Alzheimer’s Disease Research (ADR) program has awarded nearly $140 million to support promising research in fields ranging from molecular biology to genetics to epidemiology. ADR is currently supporting 133 outstanding biomedical researcher projects.

AARP’s $60 Million Investment in Dementia Research Continues to Pay Off

hand holding test tube in front of brain scans

A small team of scientists at the Akassoglou Lab is working on what could be a big breakthrough in treating dementia and other brain diseases. To read full article , click here. 

Therini Raises $17M to Bring Antibody to Myelin-damaging Protein Into Trials

Therini Bio financing round

Therini Bio announced raising $17 million in a financing round to speed the development of an antibody that might treat people with inflammatory conditions, such as multiple sclerosis (MS), associated with damage to blood vessels. To read full article, click here.

Leading the Way to Better Treatments for People with Epilepsy


Gladstone researchers harness unique tools and perspectives to pave the way to more and better treatment options for epilepsy. To read full article, click here. 

Elif Sozmen – NMSS-ABF Clinician Scientist Development Award Recipient

The National MS Society and American Brain Foundation  joined forces to support training for young clinicians committed to careers in academic medicine with an emphasis on MS clinical research. The NMSS-ABF MS Clinician-Scientist Development Award supports research for talented clinicians to address problems in MS  with the most current scientific tools.

Our image was selected for the cover of The American Journal of Pathology March 2021 Issue

Network of Co-Expressed Proteins in Cerebrospinal Fluid from Patients with CNS Lymphoma . The American Journal of Pathology, Volume 191, Issue 3, P417-588.