Toxic Cell Atlas Guides New Therapies for Neurodegeneration

October 31, 2019

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Gladstone researchers Jae Kyu Ryu, Katerina Akassoglou, and Andrew Mendiola developed a novel method to profile toxic immune cells in the brain, and used it to identify a therapeutic target for multiple sclerosis.

Tox-seq revealed subtypes of brain immune cells that produce toxic reactive oxygen in a mouse model of MS.