Nature Immunology Selected Our Image For The July 2023 Volume 24 Cover

Katerina Akassoglou and colleagues provide single-cell RNA-sequencing and phosphoproteome analyses of CNS microglia and macrophages in response to blood proteins including activated complement and fibrin. Their findings point to potential therapeutic targeting of microglia activation by immune and vascular signals.

Microglial Gi-dependent dynamics regulate brain network hyperexcitability

The immunology of blood: connecting the dots at the neurovascular interface

Fibrinogen in neurological diseases: mechanisms, imaging, therapeutics

Finding the “ubiquitous” threads in infection and autoimmune neuroinflammation